Lab Medicine

  • Location, location, location: Immunization delivery site matters

    In vaccination, a certain subpopulation of dendritic cells is vital to triggering the body’s adaptive immune system, report researchers at The Jackson Laboratory (JAX), Yale University and Astra-Zeneca. Their findings have important implications for vaccine delivery, as the usual method, intramuscular injection, is likely not the most effective way to target those dendritic cells. Vaccines train the immune system to fight…

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  • AMSBIO offers new cryopreservation medium for banking of hematopoietic stem cells

    December 1, 2017 HSC-BANKER® from AMSBIO is a new optimized GMP grade cryopreservation medium for the banking of hematopoietic stem cells isolated from umbilical cord blood, peripheral blood and bone marrow. In a comparative study on the cryopreservation of hematopoietic stem cells, performed by the Cord Blood Bank of the Japanese Red Cross Society, results using HSC-BANKER® were shown to…

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  • Immune System Targets Diverse Viruses Using the Same Small Peptide

    KNOW YOUR ENEMY: Natural killer cells, like the one attacking this larger cancer cell, can be activated by cell-surface receptors called activating KIRs. GWENOLINE BORHIS The paper M.M. Naiyer, “KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C,” Science Immunology, 2:eaal5296, 2017. Killing machines Natural killer (NK) cells help fight viral infections as part of the…

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  • Newly Developed Automated Immunoassay Analyzed

    Dipeptidyl peptidase-4 (DPP-4) may be a suitable biomarker to identify people with severe asthma who have greater activation of the…

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  • Laboratory-Developed Tests Market Driven by Cancer Treatment

    Image: The global market for laboratory-developed tests is estimated to grow by nearly 10% annually (Photo courtesy of iStock). The global market for laboratory-developed tests (LDTs) is estimated to be worth USD 13.2 billion and will grow by nearly 10% annually, driven mainly by oncology tests which will grow 60% faster than other types of LDTs. These are the latest…

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